Explore the Mechanisms

Explore cluster specific features in the context of molecular mechanisms commonly found in AD and PD. Select a set of mechanisms from different clusters and visualize the (causal) networks in detail using an interactive and dedicated visualization tool.

Download Area

Access the enrichment analyses conducted in the paper.

Cluster vs Controls

Explore connections between NeuroMMSig and observed cluster specific transcriptome + methylome changes. Visualize different paths between NeuroMMSig mechanisms and the pathways/biological processes significantly altered in each of the clusters compared to control patients.

Cluster vs Clusters

Explore connections between NeuroMMSig and observed cluster specific transcriptome + methylome changes. Visualize different paths between NeuroMMSig mechanisms and the pathways/biological processes significantly altered in each of the clusters compared to the other clusters.