Linking Disease Mechanisms with Biological Processes and Pathways Identified from Data

The table below shows the different pathways and biological processes (column 2) that has been associated to the identified clusters. These clusters have been characterized based on disease-specific mechanisms coming from NeuroMMSig (column 7). By selecting the combination of pathways/biological processes and NeuroMMSig mechanisms, you can explore how the mechanisms in each cluster are linked to the pathways and biological processes. Click in this info icon to learn the methodology behind our approach.

Cluster Pathways/Biological Process Condition Dataset Omics Type False Discovery Rate (FDR) NeuroMMSig Mechanism Cluster Gene associated with the NeuroMMSig Mechanism Explore
1 cell cycle process AD ROSMAP RNAseq 0.03 Akt subgraph AKT1
1 cell cycle AD ROSMAP RNAseq 0.03 Akt subgraph AKT1
1 MAPK signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Akt subgraph AKT1
1 Valine, leucine and isoleucine degradation - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Akt subgraph AKT1
1 Protein processing in endoplasmic reticulum - Homo sapiens (human) AD ROSMAP Methy 0.04 Akt subgraph AKT1
2 cell death PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 cell proliferation PD PPMI RNAseq 0.05 Cell cycle subgraph TP53
2 cell proliferation PD PPMI RNAseq 0.05 Caspase subgraph CASP3,NLRP3
2 cognition PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 cognition PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 cytokine production PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 cytokine production PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 inflammatory response PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 inflammatory response PD PPMI RNAseq 0.02 Interleukin signaling subgraph IL1B, IL6
2 inflammatory response PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 innate immune response PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 innate immune response PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 neurogenesis PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 neurogenesis PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 neurogenesis PD PPMI RNAseq 0.02 MAPK subgraph MAPK9,MAPK8
2 synaptic vesicle localization PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 synaptic vesicle localization PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 Aldosterone-regulated sodium reabsorption - Homo sapiens (human) PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 Aldosterone-regulated sodium reabsorption - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 Apoptosis - Homo sapiens (human) PD PPMI RNAseq 0.05 Cell cycle subgraph TP53
2 Apoptosis - Homo sapiens (human) PD PPMI RNAseq 0.05 Caspase subgraph CASP3,NLRP3
2 Apoptosis - Homo sapiens (human) PD PPMI RNAseq 0.05 MAPK subgraph MAPK9,MAPK8
2 Chronic myeloid leukemia - Homo sapiens (human) PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 Chronic myeloid leukemia - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 Complement and coagulation cascades - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 Complement and coagulation cascades - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 Cytokine-cytokine receptor interaction - Homo sapiens (human) PD PPMI RNAseq 0.0 Cell cycle subgraph TP53
2 Cytokine-cytokine receptor interaction - Homo sapiens (human) PD PPMI RNAseq 0.0 Caspase subgraph CASP3,NLRP3
2 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) PD PPMI RNAseq 0.0 Cell cycle subgraph TP53
2 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) PD PPMI RNAseq 0.0 Caspase subgraph CASP3,NLRP3
2 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human) PD PPMI RNAseq 0.0 MAPK subgraph MAPK9,MAPK8
2 ErbB signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 GSK3 subgraph GSK3B
2 ErbB signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 ErbB signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 ErbB signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 MAPK subgraph MAPK9,MAPK8
2 Glioma - Homo sapiens (human) PD PPMI RNAseq 0.04 Cell cycle subgraph TP53
2 Glioma - Homo sapiens (human) PD PPMI RNAseq 0.04 Caspase subgraph CASP3,NLRP3
2 Insulin signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.02 GSK3 subgraph GSK3B
2 Insulin signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.02 Cell cycle subgraph TP53
2 Insulin signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
2 Insulin signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.02 MAPK subgraph MAPK9,MAPK8
2 Intestinal immune network for IgA production - Homo sapiens (human) PD PPMI RNAseq 0.03 Cell cycle subgraph TP53
2 Intestinal immune network for IgA production - Homo sapiens (human) PD PPMI RNAseq 0.03 Caspase subgraph CASP3,NLRP3
2 JAK-STAT signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 JAK-STAT signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 Pancreatic cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 Pancreatic cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 Pancreatic cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 MAPK subgraph MAPK9,MAPK8
2 Prostate cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 GSK3 subgraph GSK3B
2 Prostate cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 Prostate cancer - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 Toll-like receptor signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Cell cycle subgraph TP53
2 Toll-like receptor signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 Caspase subgraph CASP3,NLRP3
2 Toll-like receptor signaling pathway - Homo sapiens (human) PD PPMI RNAseq 0.01 MAPK subgraph MAPK9,MAPK8
2 microtubule cytoskeleton organization PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 microtubule cytoskeleton organization PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 autophagy PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 autophagy PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 regulation of autophagy PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 regulation of autophagy PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 cell maturation PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 cell maturation PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 ATP biosynthetic process PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 ATP biosynthetic process PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 steroid metabolic process PD PPMI Methy 0.01 Cell cycle subgraph TP53
2 steroid metabolic process PD PPMI Methy 0.01 Caspase subgraph CASP3,NLRP3
2 positive regulation of cell cycle PD PPMI Methy 0.01 Cell cycle subgraph TP53
2 positive regulation of cell cycle PD PPMI Methy 0.01 Caspase subgraph CASP3,NLRP3
2 cellular response to heat PD PPMI Methy 0.01 Cell cycle subgraph TP53
2 cellular response to heat PD PPMI Methy 0.01 Caspase subgraph CASP3,NLRP3
2 Alzheimer disease - Homo sapiens (human) PD PPMI Methy 0.02 GSK3 subgraph GSK3B
2 Alzheimer disease - Homo sapiens (human) PD PPMI Methy 0.02 Cell cycle subgraph TP53
2 Alzheimer disease - Homo sapiens (human) PD PPMI Methy 0.02 Tau protein subgraph MAPT
2 Alzheimer disease - Homo sapiens (human) PD PPMI Methy 0.02 Caspase subgraph CASP3,NLRP3
2 Hepatitis C - Homo sapiens (human) PD PPMI Methy 0.0 GSK3 subgraph GSK3B
2 Hepatitis C - Homo sapiens (human) PD PPMI Methy 0.0 Cell cycle subgraph TP53
2 Hepatitis C - Homo sapiens (human) PD PPMI Methy 0.0 Caspase subgraph CASP3,NLRP3
2 Oocyte meiosis - Homo sapiens (human) PD PPMI Methy 0.02 Cell cycle subgraph TP53
2 Oocyte meiosis - Homo sapiens (human) PD PPMI Methy 0.02 Caspase subgraph CASP3,NLRP3
2 innate immune response AD ROSMAP RNAseq 0.01 Tau protein subgraph MAPT
2 innate immune response AD ROSMAP RNAseq 0.01 Cyclin-CDK subgraph CDK5
2 innate immune response AD ROSMAP RNAseq 0.01 DYRK1A subgraph DYRK1A
2 innate immune response AD ROSMAP RNAseq 0.01 Interleukin signaling subgraph IL1B, IL6
2 innate immune response AD ROSMAP RNAseq 0.01 Caspase subgraph NLRP3,CASP3, BCL2
2 innate immune response AD ROSMAP RNAseq 0.01 Bcl-2 subgraph MAPK8,BCL2
2 lipid metabolic process AD ROSMAP RNAseq 0.01 Tau protein subgraph MAPT
2 lipid metabolic process AD ROSMAP RNAseq 0.01 Cyclin-CDK subgraph CDK5
2 lipid metabolic process AD ROSMAP RNAseq 0.01 DYRK1A subgraph DYRK1A
2 lipid metabolic process AD ROSMAP RNAseq 0.01 Interleukin signaling subgraph IL1B, IL6
2 lipid metabolic process AD ROSMAP RNAseq 0.01 Caspase subgraph NLRP3,CASP3, BCL2
2 lipid metabolic process AD ROSMAP RNAseq 0.01 Bcl-2 subgraph MAPK8,BCL2
2 phagocytosis AD ROSMAP RNAseq 0.03 Tau protein subgraph MAPT
2 phagocytosis AD ROSMAP RNAseq 0.03 Cyclin-CDK subgraph CDK5
2 phagocytosis AD ROSMAP RNAseq 0.03 DYRK1A subgraph DYRK1A
2 phagocytosis AD ROSMAP RNAseq 0.03 Interleukin signaling subgraph IL1B, IL6
2 phagocytosis AD ROSMAP RNAseq 0.03 Caspase subgraph NLRP3,CASP3, BCL2
2 phagocytosis AD ROSMAP RNAseq 0.03 Bcl-2 subgraph MAPK8,BCL2
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 Tau protein subgraph MAPT
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 Cyclin-CDK subgraph CDK5
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 DYRK1A subgraph DYRK1A
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 Interleukin signaling subgraph IL1B, IL6
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 Caspase subgraph NLRP3,CASP3, BCL2
2 regulation of phagocytosis AD ROSMAP RNAseq 0.04 Bcl-2 subgraph MAPK8,BCL2
2 dendrite development AD ROSMAP RNAseq 0.05 Tau protein subgraph MAPT
2 dendrite development AD ROSMAP RNAseq 0.05 Cyclin-CDK subgraph CDK5
2 dendrite development AD ROSMAP RNAseq 0.05 DYRK1A subgraph DYRK1A
2 dendrite development AD ROSMAP RNAseq 0.05 Interleukin signaling subgraph IL1B, IL6
2 dendrite development AD ROSMAP RNAseq 0.05 Caspase subgraph NLRP3,CASP3, BCL2
2 dendrite development AD ROSMAP RNAseq 0.05 Bcl-2 subgraph MAPK8,BCL2
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 Tau protein subgraph MAPT
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 Cyclin-CDK subgraph CDK5
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 DYRK1A subgraph DYRK1A
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 Interleukin signaling subgraph IL1B, IL6
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 Caspase subgraph NLRP3,CASP3, BCL2
2 Notch signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.02 Bcl-2 subgraph MAPK8,BCL2
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Tau protein subgraph MAPT
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Cyclin-CDK subgraph CDK5
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 DYRK1A subgraph DYRK1A
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Interleukin signaling subgraph IL1B, IL6
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Caspase subgraph NLRP3,CASP3, BCL2
2 Hematopoietic cell lineage - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Bcl-2 subgraph MAPK8,BCL2
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Tau protein subgraph MAPT
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Cyclin-CDK subgraph CDK5
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 DYRK1A subgraph DYRK1A
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Interleukin signaling subgraph IL1B, IL6
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Caspase subgraph NLRP3,CASP3, BCL2
2 Primary bile acid biosynthesis - Homo sapiens (human) AD ROSMAP RNAseq 0.03 Bcl-2 subgraph MAPK8,BCL2
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 Tau protein subgraph MAPT
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 Cyclin-CDK subgraph CDK5
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 DYRK1A subgraph DYRK1A
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 Interleukin signaling subgraph IL1B, IL6
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 Caspase subgraph NLRP3,CASP3, BCL2
2 receptor-mediated endocytosis AD ROSMAP Methy 0.02 Bcl-2 subgraph MAPK8,BCL2
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 Tau protein subgraph MAPT
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 Cyclin-CDK subgraph CDK5
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 DYRK1A subgraph DYRK1A
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 Interleukin signaling subgraph IL1B, IL6
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 Caspase subgraph NLRP3,CASP3, BCL2
2 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.04 Bcl-2 subgraph MAPK8,BCL2
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 Tau protein subgraph MAPT
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 Cyclin-CDK subgraph CDK5
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 DYRK1A subgraph DYRK1A
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 Interleukin signaling subgraph IL1B, IL6
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 Caspase subgraph NLRP3,CASP3, BCL2
2 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.04 Bcl-2 subgraph MAPK8,BCL2
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 Tau protein subgraph MAPT
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 Cyclin-CDK subgraph CDK5
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 DYRK1A subgraph DYRK1A
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 Interleukin signaling subgraph IL1B, IL6
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 Caspase subgraph NLRP3,CASP3, BCL2
2 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.04 Bcl-2 subgraph MAPK8,BCL2
3 cellular respiration PD PPMI RNAseq 0.04 Matrix metalloproteinase subgraph TOMM40
3 cellular respiration PD PPMI RNAseq 0.04 Synuclein subgraph SNCA
3 cellular respiration PD PPMI RNAseq 0.04 CRH subgraph CRH
3 cellular respiration PD PPMI RNAseq 0.04 Caspase subgraph CASP3,NLRP3
3 Cardiac muscle contraction - Homo sapiens (human) PD PPMI RNAseq 0.02 Matrix metalloproteinase subgraph TOMM40
3 Cardiac muscle contraction - Homo sapiens (human) PD PPMI RNAseq 0.02 Synuclein subgraph SNCA
3 Cardiac muscle contraction - Homo sapiens (human) PD PPMI RNAseq 0.02 CRH subgraph CRH
3 Cardiac muscle contraction - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
3 Huntington disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Matrix metalloproteinase subgraph TOMM40
3 Huntington disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Synuclein subgraph SNCA
3 Huntington disease - Homo sapiens (human) PD PPMI RNAseq 0.02 CRH subgraph CRH
3 Huntington disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
3 Oxidative phosphorylation - Homo sapiens (human) PD PPMI RNAseq 0.02 Matrix metalloproteinase subgraph TOMM40
3 Oxidative phosphorylation - Homo sapiens (human) PD PPMI RNAseq 0.02 Synuclein subgraph SNCA
3 Oxidative phosphorylation - Homo sapiens (human) PD PPMI RNAseq 0.02 CRH subgraph CRH
3 Oxidative phosphorylation - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
3 Parkinson disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Matrix metalloproteinase subgraph TOMM40
3 Parkinson disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Synuclein subgraph SNCA
3 Parkinson disease - Homo sapiens (human) PD PPMI RNAseq 0.02 CRH subgraph CRH
3 Parkinson disease - Homo sapiens (human) PD PPMI RNAseq 0.02 Caspase subgraph CASP3,NLRP3
3 Galactose metabolism - Homo sapiens (human) PD PPMI RNAseq 0.04 Matrix metalloproteinase subgraph TOMM40
3 Galactose metabolism - Homo sapiens (human) PD PPMI RNAseq 0.04 Synuclein subgraph SNCA
3 Galactose metabolism - Homo sapiens (human) PD PPMI RNAseq 0.04 CRH subgraph CRH
3 Galactose metabolism - Homo sapiens (human) PD PPMI RNAseq 0.04 Caspase subgraph CASP3,NLRP3
3 Glycolysis / Gluconeogenesis - Homo sapiens (human) PD PPMI RNAseq 0.05 Matrix metalloproteinase subgraph TOMM40
3 Glycolysis / Gluconeogenesis - Homo sapiens (human) PD PPMI RNAseq 0.05 Synuclein subgraph SNCA
3 Glycolysis / Gluconeogenesis - Homo sapiens (human) PD PPMI RNAseq 0.05 CRH subgraph CRH
3 Glycolysis / Gluconeogenesis - Homo sapiens (human) PD PPMI RNAseq 0.05 Caspase subgraph CASP3,NLRP3
3 Tight junction - Homo sapiens (human) PD PPMI RNAseq 0.05 Matrix metalloproteinase subgraph TOMM40
3 Tight junction - Homo sapiens (human) PD PPMI RNAseq 0.05 Synuclein subgraph SNCA
3 Tight junction - Homo sapiens (human) PD PPMI RNAseq 0.05 CRH subgraph CRH
3 Tight junction - Homo sapiens (human) PD PPMI RNAseq 0.05 Caspase subgraph CASP3,NLRP3
3 long term synaptic depression AD ROSMAP RNAseq 0.02 Syndecan subgraph SDC2
3 long term synaptic depression AD ROSMAP RNAseq 0.02 APOE subgraph APOE
3 long term synaptic depression AD ROSMAP RNAseq 0.02 Endosomal lysosomal subgraph PICALM
3 long term synaptic depression AD ROSMAP RNAseq 0.02 Caspase subgraph NLRP3,CASP3, BCL2
3 long term synaptic depression AD ROSMAP RNAseq 0.02 XIAP subgraph CASP3
3 long term synaptic depression AD ROSMAP RNAseq 0.02 Bcl-2 subgraph MAPK8,BCL2
3 mitochondrion organization AD ROSMAP RNAseq 0.03 Syndecan subgraph SDC2
3 mitochondrion organization AD ROSMAP RNAseq 0.03 APOE subgraph APOE
3 mitochondrion organization AD ROSMAP RNAseq 0.03 Endosomal lysosomal subgraph PICALM
3 mitochondrion organization AD ROSMAP RNAseq 0.03 Caspase subgraph NLRP3,CASP3, BCL2
3 mitochondrion organization AD ROSMAP RNAseq 0.03 XIAP subgraph CASP3
3 mitochondrion organization AD ROSMAP RNAseq 0.03 Bcl-2 subgraph MAPK8,BCL2
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 Syndecan subgraph SDC2
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 APOE subgraph APOE
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 Endosomal lysosomal subgraph PICALM
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 Caspase subgraph NLRP3,CASP3, BCL2
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 XIAP subgraph CASP3
3 negative regulation of neuron apoptotic process AD ROSMAP RNAseq 0.03 Bcl-2 subgraph MAPK8,BCL2
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Syndecan subgraph SDC2
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 APOE subgraph APOE
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Endosomal lysosomal subgraph PICALM
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Caspase subgraph NLRP3,CASP3, BCL2
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 XIAP subgraph CASP3
3 Acute myeloid leukemia - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Bcl-2 subgraph MAPK8,BCL2
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Syndecan subgraph SDC2
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 APOE subgraph APOE
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Endosomal lysosomal subgraph PICALM
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Caspase subgraph NLRP3,CASP3, BCL2
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 XIAP subgraph CASP3
3 Focal adhesion - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Bcl-2 subgraph MAPK8,BCL2
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Syndecan subgraph SDC2
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 APOE subgraph APOE
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Endosomal lysosomal subgraph PICALM
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Caspase subgraph NLRP3,CASP3, BCL2
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 XIAP subgraph CASP3
3 Bladder cancer - Homo sapiens (human) AD ROSMAP RNAseq 0.04 Bcl-2 subgraph MAPK8,BCL2
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Syndecan subgraph SDC2
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 APOE subgraph APOE
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Endosomal lysosomal subgraph PICALM
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Caspase subgraph NLRP3,CASP3, BCL2
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 XIAP subgraph CASP3
3 ECM-receptor interaction - Homo sapiens (human) AD ROSMAP RNAseq 0.0 Bcl-2 subgraph MAPK8,BCL2
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Syndecan subgraph SDC2
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 APOE subgraph APOE
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Endosomal lysosomal subgraph PICALM
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Caspase subgraph NLRP3,CASP3, BCL2
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 XIAP subgraph CASP3
3 Leukocyte transendothelial migration - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Bcl-2 subgraph MAPK8,BCL2
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Syndecan subgraph SDC2
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 APOE subgraph APOE
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Endosomal lysosomal subgraph PICALM
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Caspase subgraph NLRP3,CASP3, BCL2
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 XIAP subgraph CASP3
3 Adipocytokine signaling pathway - Homo sapiens (human) AD ROSMAP RNAseq 0.01 Bcl-2 subgraph MAPK8,BCL2
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 Syndecan subgraph SDC2
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 APOE subgraph APOE
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 Endosomal lysosomal subgraph PICALM
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 Caspase subgraph NLRP3,CASP3, BCL2
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 XIAP subgraph CASP3
3 regulation of neuron apoptotic process AD ROSMAP Methy 0.02 Bcl-2 subgraph MAPK8,BCL2
3 T cell activation AD ROSMAP Methy 0.03 Syndecan subgraph SDC2
3 T cell activation AD ROSMAP Methy 0.03 APOE subgraph APOE
3 T cell activation AD ROSMAP Methy 0.03 Endosomal lysosomal subgraph PICALM
3 T cell activation AD ROSMAP Methy 0.03 Caspase subgraph NLRP3,CASP3, BCL2
3 T cell activation AD ROSMAP Methy 0.03 XIAP subgraph CASP3
3 T cell activation AD ROSMAP Methy 0.03 Bcl-2 subgraph MAPK8,BCL2
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 Syndecan subgraph SDC2
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 APOE subgraph APOE
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 Endosomal lysosomal subgraph PICALM
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 Caspase subgraph NLRP3,CASP3, BCL2
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 XIAP subgraph CASP3
3 negative regulation of neuron apoptotic process AD ROSMAP Methy 0.03 Bcl-2 subgraph MAPK8,BCL2
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 Syndecan subgraph SDC2
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 APOE subgraph APOE
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 Endosomal lysosomal subgraph PICALM
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 Caspase subgraph NLRP3,CASP3, BCL2
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 XIAP subgraph CASP3
3 Axon guidance - Homo sapiens (human) AD ROSMAP Methy 0.01 Bcl-2 subgraph MAPK8,BCL2
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 Syndecan subgraph SDC2
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 APOE subgraph APOE
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 Endosomal lysosomal subgraph PICALM
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 Caspase subgraph NLRP3,CASP3, BCL2
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 XIAP subgraph CASP3
3 Cell adhesion molecules (CAMs) - Homo sapiens (human) AD ROSMAP Methy 0.01 Bcl-2 subgraph MAPK8,BCL2
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 Syndecan subgraph SDC2
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 APOE subgraph APOE
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 Endosomal lysosomal subgraph PICALM
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 Caspase subgraph NLRP3,CASP3, BCL2
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 XIAP subgraph CASP3
3 Pathways in cancer - Homo sapiens (human) AD ROSMAP Methy 0.01 Bcl-2 subgraph MAPK8,BCL2
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Syndecan subgraph SDC2
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 APOE subgraph APOE
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Endosomal lysosomal subgraph PICALM
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Caspase subgraph NLRP3,CASP3, BCL2
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 XIAP subgraph CASP3
3 Calcium signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Bcl-2 subgraph MAPK8,BCL2
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Syndecan subgraph SDC2
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 APOE subgraph APOE
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Endosomal lysosomal subgraph PICALM
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Caspase subgraph NLRP3,CASP3, BCL2
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 XIAP subgraph CASP3
3 Wnt signaling pathway - Homo sapiens (human) AD ROSMAP Methy 0.02 Bcl-2 subgraph MAPK8,BCL2
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 Syndecan subgraph SDC2
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 APOE subgraph APOE
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 Endosomal lysosomal subgraph PICALM
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 Caspase subgraph NLRP3,CASP3, BCL2
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 XIAP subgraph CASP3
3 Melanogenesis - Homo sapiens (human) AD ROSMAP Methy 0.04 Bcl-2 subgraph MAPK8,BCL2
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 Syndecan subgraph SDC2
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 APOE subgraph APOE
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 Endosomal lysosomal subgraph PICALM
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 Caspase subgraph NLRP3,CASP3, BCL2
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 XIAP subgraph CASP3
3 Tight junction - Homo sapiens (human) AD ROSMAP Methy 0.05 Bcl-2 subgraph MAPK8,BCL2
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 Syndecan subgraph SDC2
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 APOE subgraph APOE
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 Endosomal lysosomal subgraph PICALM
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 Caspase subgraph NLRP3,CASP3, BCL2
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 XIAP subgraph CASP3
3 Regulation of actin cytoskeleton - Homo sapiens (human) AD ROSMAP Methy 0.05 Bcl-2 subgraph MAPK8,BCL2